Breaking Barriers: Top Companies in Healthcare Innovating for Patient Access

by | Oct 28, 2025 | Life Science Copywriting

Achieving patient access at scale

This edition of the Foculus 50 Spotlight Series highlights healthcare innovators achieving patient access at scale. They all share the mission of increasing healthcare reach for the greatest number of people, including those facing barriers to care. As a reminder, Foculus 50 Healthcare Innovators were selected for meeting one or more of the following criteria.

  1. Patient Impact: How many patients directly benefit from the organization’s solution?
  2. Collaboration: How well does the company achieve results by working with other healthcare and patient-community stakeholders?
  3. Adaptability: Has the company shown flexibility and the ability to pivot in response to challenges and patient needs?
  4. Patient Experience in R&D: Do patients meaningfully contribute to R&D, feedback, and design cycles?
  5. Access: Can the innovation reach the greatest number of people—including those with barriers to care?

Syngage AI, our newly launched SaaS platform, is designed to enhance this impact by transforming business development with meaningful, data-driven conversations so sellers can reach more buyers with relevant, research-supported messaging across life sciences and healthcare. Below, review the Foculus 50 companies leading the charge for access, each ordered by their impact and accompanied by their LinkedIn company and executive profile URLs to facilitate true, research-driven outreach.​

Companies with Greatest Impact on Access

Operation Smile

Operation Smile stands out as a global non-profit bridging gaps in access to essential surgeries and healthcare, beginning with cleft lip/palate surgeries. Through a distributed volunteer model and partnerships across borders, they deliver free surgical and care solutions to underserved communities affected by congenital facial deformities. Impact: Directly reaches disadvantaged populations worldwide, breaking both geographic and financial barriers.

LegWorks

LegWorks, Inc. is a social enterprise focused on accessible prosthetic solutions, designing durable, high-functioning devices for amputees in both developed and developing markets. Their All-Terrain Knee is recognized for quality and affordability, expanding access to mobility for those who might otherwise go without. Impact: Expands access to high-quality prosthetics for individuals in lower-resource settings.

Reperio Health

Reperio Health reimagines preventive care through nationwide, at-home, clinical-grade health screening kits paired with instant virtual consultations. Their model removes barriers of geography, scheduling, and cost, putting comprehensive preventive care within reach of more Americans. Impact: Scalable solution expanding preventive healthcare access to millions via telehealth and AI-driven diagnostics.

Human Longevity, Inc.

Human Longevity, Inc. uses genomics and advanced diagnostics to expand preventive, precision healthcare globally, with clinics in the US and China and further expansion planned. Their AI-enabled, data-driven approach puts advanced health intelligence within reach of wider populations, including underserved communities. Impact: Reduces barriers to personalized, preventive care across borders through technology.​

Garwood Medical Devices

Garwood Medical Devices delivers technology for infection control and wound healing, notably with FDA Breakthrough Device designation for their BioPrax™ electronic device. Their active bandage and electronic solutions support vulnerable patient populations where infections pose a major threat and care access is limited. Impact: Enables advanced infection prevention in hard-to-reach, high-need patient groups.​

Puzzle Medical Devices

Puzzle Medical Devices offers a minimally invasive, modular heart pump for advanced heart failure patients, expanding access to cardiac care for those unable to undergo open-heart surgery. Their solution provides safer, less resource-intensive interventions suitable for hospitals with limited surgical capabilities. Impact: Bridges cardiac care gaps for at-risk heart failure patients globally.​

Vori Health

Vori Health disrupts musculoskeletal care with a holistic, virtual-first approach, combining rehab medicine, therapy, coaching, imaging, and more in one service. They reach patients where they are and prioritize underserved communities facing access issues in traditional healthcare systems. Impact: Virtual model expands access for orthopedic and chronic pain patients, reducing disparities.​

Francis Medical

Francis Medical introduces vapor-based tumor ablation therapy for prostate, kidney, and bladder cancers, streamlining cancer care to make it less invasive and more accessible—even in settings with limited surgical infrastructure. Focused on accelerating FDA clearance and reimbursement strategies for broad patient impact. Impact: Minimally invasive oncology tech making cancer care feasible for more patients.​

Hemotune AG

Hemotune AG tackles systemic conditions with magnetic blood purification, developing scalable technology to reach critically ill patients, including those in regions with limited ICU resources. The company’s breakthrough is poised to democratize access to advanced therapies for sepsis globally. Impact: Opens up life-saving treatment for severe infections in low-resource hospitals.

Why These Companies Were Chosen

These organizations made the list of Foculus 50 Healthcare Innovators because they lead on access by deploying scalable models, innovative tech, and adaptable care platforms that reach patients otherwise left behind. 

Their business models and social missions align with Syngage AI’s mission to empower outreach and engagement for those driving healthcare innovation at scale.

Syngage AI equips teams to unlock patient-centered impact

Syngage AI is designed to amplify the mission of healthcare innovators, equipping sales and marketing teams to reach the executives, buyers, and partners who shape life sciences access. Use Syngage AI powered insights to connect with top leaders, share data-driven value, and build relationships that unlock patient-centric impact for those who need it most.

References

  1. https://foculusmarketing.com/foculus-50-healthcare-innovators-usher-in-a-new-patient-centered-age/
  2. https://www.forbes.com/profile/brandon-burke/
  3. https://www.linkedin.com/posts/travisrush_the-future-of-preventive-care-is-now-and-activity-7330933819543289857-ljw_
  4. https://www.businesswire.com/news/home/20251014537865/en/Reperio-Health-Deepens-National-Footprint-Adds-Industry-Vets-to-Drive-At-Home-Preventive-Care-Access
  5. https://www.boringbusinessnerd.com/startups/vori-health
  6. https://www.mmm-online.com/home/channel/people-moves/vori-health-adds-five-to-executive-team/
  7. https://www.linkedin.com/posts/hemotune_hemotune-magnetic-blood-purification-activity-7315372893993914370-1KPB
  8. https://www.planetdds.com/blog/legwork-strengthens-executive-team-with-addition-of-alex-cuevas/
  9. https://www.planetdds.com/blog/legwork-grows-executive-team-with-new-chief-financial-officer-andy-wynne/
  10. https://www.linkedin.com/posts/puzzlemedicaldevices_puzzle-medical-devices-inc-announces-the-activity-6952987637821399040-i1rv